Significant strides have been made in the development of in vitro systems for disease modelling. However, the requirement of spatially defined microenvironment control limits the generation of relevant models. To address these limitations Lydia Moll from Cellectricon AB and the Karolinska Institute in Sweden have collaborated with the company Fluicell AB. They have published their cell printing approach in Nature Scientific Reports. Here, they present a biological cell printing approach that employs open-volume microfluidics to enable positioning of individual cells in complex 2D and 3D patterns. Lydia and the Cellectricon team contributed by investigating the possibilities to use the 3D single-cell bioprinting platform to print neurons and ultimately develop a system that could provide potential to address diseases like chronic pain, Alzheimer’s or Parkinson’s disease.
The paper is available here: https://www.nature.com/articles/s41598-020-74191-w#additional-information.